All the crap you never needed

May 31 2024 The Rainman’s court Sacks + Chamath hosting fund raise for Trump Trump leading in the polls He might come on the pod also They kinda already did pod + fund raiser for RFK Jr, Dean Phillips, Vivek Chris Christie came on the pod but they didn’t do official fund raiser They would do Biden also (at least Chamath would) They want to model being able to associate with friends who have different political opinions Chamath has donated to Democrats massively They are hoping to fight the preference falsification issue where people secretly support Trump and don’t want to admit it Jason thinks Dems will switch their candidate soon Sacks is skeptical about that House COVID-19 investigation Bipartisan investigation Focused on communication between NIH officials and Eco Health Alliance Peter Daszak mentioned Fauci mentioned He even pushed back against Rand Paul when asked about it some time ago Does the effort to try and stop the problem actually cause the problem? Post SARS efforts ...

May 24 2024 General AI Hospital Sam Altman Mira Murati Ilya Sutskever Scarlett Johansson Scarlett Johansson - OpenAI controversy Sam approached her to use her voice - she refused Their latest bot “Sky” apparently has similar voice They have removed the voice now The actress who provided the voice is someone else apparently Challenging situation for both sides when company/film/app wants to use a particular celebrity’s voice/likeness OpenAI employee exit agreements Lots of apparent restrictions Super alignment team from OpenAI leaves Ilya, Jan Leike, etc Apparently there are some differences over safety’s importance, etc? Or maybe that’s speculation NVidia smashes earnings Rapid rise Might want to be careful and avoid Intel’s fate when they got big into dotcom boom and since haven’t gone up much Or will it be like Cisco? Cisco got commoditized They might have a much better moat than Cisco - their technology is harder to copy probably...

May 17 2024 Phil Hellmuth birthday weekend Besties having fun OpenAI GPT-4o Multi modal Amazing use cases - translation, teaching, etc “Facebook” of AI has yet to be created seems like - maybe OpenAI is doing these demos to shore up customer usage Models are getting cheaper and better Lot of startups’ product roadmaps and R&D went out the window - start a company now, last 2-5 years of work is gone Where does model innovation end and your innovation begin? They should do open source Facebook did the same thing with Open Compute Sacks’ Glue AI features Can do queries, transcripts, etc They use ragie.ai No channels Promptless - you don’t even have to @mention any specific dataset bot - TBD Ohalo Boosted breeding - figured out how to get 100% of genes from mother and father plants 100% of genes means no random outcomes Yield on some of these plants goes up 50-100% or more Better yield Polyploid - multiple sets of chromosomes Works in plants, ...

May 10 2024 Sam Altman joins All In!! Seqouia scout with Jason YC OpenAI GPT-5 Might just be better GPT-4 Optimistic about speed and cost - because that’s what people want Thinks open source and closed source can co-exist Very interested in some kind of AI-powered device - will it be a phone? Phones are already great so something else has to be much better Thinks iPhone is the best computing device ever made Agents Wants the world’s greatest assistant Another approach is alter-ego Wants to design a world that can be equally used by humans and AIs Voice, multi modal etc is interesting But multiple interfaces will probably always be there Excited about potential for faster and better scientific discovery Training vs Inference Training data will be less important going forward and inference will be more going forward AI regulation Skeptical about details for minutiae But backs the need for regulation - if we don’t do that we would be irresponsible Like how...

May 3 2024 Sheryl Sandberg joins the show! Sacks last minute board meeting She’s a complete rockstar Google - $20M to $22B Facebook - $250M to ~$170B Dave Goldberg - her husband was FakeChamath handle on twitter She has produced a documentary About Oct 7 and Hamas attacks Shocked how people were denying what happened in the attacks Especially the sexual violence Sexual violence is a war crime Campus protests Kids are gravitating to these because of social dynamic - they feel attached to something OpenCRISPR-1 Profluent Bio based in Berkeley Open source AI gene editing