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All In Interview - Marty Makary - Recap and Notes - January 15 2026

January 15 2026 FDA Commissioner In San Francisco for JPM Health Conference Hospital Price Transparency Sociology of Medical Dogma FDA wastage 2000 HR people before he got there 1500 IT people before he got there 20000 employees total before he got there Previous commissioner’s first priority was to fight misinformation - new priority is to deliver better care and healthier food Accelerating drug approvals Eliminating/reducing animal trials Animal testing might not help - in fact can hurt Computational models can fix it Might want to introduce continuous trials Planning to allow use of Bayesian statistics Safety-ism has hurt people by delaying access to medication Surprises Each of the centers had their own silos - a guy would move documents from 1 center to another because of lawyer requirements 1 guy was the ink guy on the fax machine All cleaned up Food pyramid Everyone knows it was backwards - was wrong - childhood obesity was off the charts Too much...

All In Interview - Bob Sternfels and Hemant Taneja - Recap and Notes - January 14 2026

January 14 2026 Bob Sternfels - McKinsey Hemant Taneja - General Catalyst CEO AI disruption McKinsey hiring changing - more client facing, less non-client facing Kids need to learn how to ask the right questions instead of just focusing on solving hard math problems Robotics and automation will carry the day Jason giving giant infomercial for Tesla Optimus

All In Interview - Adam Carolla - Recap and Notes - January 12 2026

January 12 2026 First ever ad read - Paypal Open by Friedberg Palisades fire recap 1 year ago 6837 structures destroyed - ~5000 homes As of Nov 2025 only 1 home has been rebuilt Carolla lives in Malibu - saw the fire breakout as it happened - evacuated later that night Early life in construction - familiar with the issue Has encountered a lot of bureaucracy over the years California Coastal Commission and other departments make it hard to build - permitting process is insane Diagnosis Blames what he calls Gyno fascism - safetyism and environmentalism They hide behind the shield of safety and don’t think about the second order effects of making everything “safer” Blames Barbara Ferrer for shutdown Shows how teachers unions are very powerful Rochelle Walensky had to walk back her covid shutdown comments Why are they allowed to elect politicians? Shows how absurd it is that the LA Times would endorse a political candidate - then how can you trust their reporting on...

All In Podcast Episode 257 Recap and Notes January 9 2026

January 9 2026 CA Exodus Sacks in Austin, Texas Moved in December Austin office for Craft Ventures Chamath started the process in December - nothing decided yet Sacks’s broker helping Chamath find a place A lot of people are hedging their bets Larry Page going to Florida maybe Chamath claims $0.5T net worth of his friends have left Even Reid Hoffman thinks the proposed wealth tax is insane This is not going away - the leftists want it to go through The problem is the fraud - fix the fraud first then decide on taxes Sergey also probably left CA is also levying more taxes based on super voting - this is why the Google founders likely left Seizing assets tax - does it get on the ballot and does it go through Friedberg - No, and so No Mamdani and Cea Weaver communist rhetoric going up Collectivism over individualism Seize people’s property Predictions show Template Last year Friedberg Gavin Jason Chamath This year Friedberg Jason Chamath Sacks ...

All In Interview - Howard Lutnick - Recap and Notes - January 8 2026

Jan 8 2026 AirForce One stories Commerce Secretary Howard Lutnick Last year look back on experience coming in Outcome driven - working hard and failing is failure, not working and succeeding is success In department - cut 52000 → 40000 people Government has typically many specialists, not generalists - Secretary’s job is to put those together Scope BIS - Bureau of Industry and Security Tariffs Import/Export assist model (Boeing closely follows them for example) NTIA - Telecom, Spectrum, 6G?, AI GDP published - use the census, business census Publish on the blockchain Patent office NOAA - Oceans and Atmosphere Now there is Office of space commerce Tariffs Trade deficit is not buying stuff from a supermarket Its actually them owning you 1985 US owned more of the world - $148B 2026 they own more of us - $26T Trade deals Japan Hard to open them up culturally, economically, socially, technically (all of them) So slapped 25% tariffs Japan auto industr...

All In Interview - Scott Bessent - Recap and Notes - December 22 2025

December 22 2025 Budget Deficit - goal was 3% Came down from 1.8T to 1.78T (estimated was 2.0T which would have been much worse) 40% of government spending occurred in the 4th quarter of 2024 during Biden administration trying to convince voters to their side Projecting $200-$300B contraction Year nominal growth of 6% Hoping to get it down to mid 5s Tariffs Alan Greenspan did a great job in the 90s and during Clinton years economy was roaring Folks were even worried there wouldn’t be enough government debt to service some financial actors SF Fed with 150 years of data shows that tariffs are disinflationary and do not cause inflation (see study) Tariff policy is part of national security Fentanyl imports dropping by putting pressure on China Trump retaliated to Chinese rare earth tariffs with his own tariffs Chinese won’t stop producing because of tariffs - their economy is based on volume Current tariffs is to cause a rebalancing of the economy - over time it shou...